BDBM50044657 CHEMBL3353347::US10358436, Example A24::US9907800, Example A24

SMILES CN(C)Cc1ccc(\C=C\c2n[nH]c3cc(ccc23)[C@@H]2C[C@@]22C(=O)Nc3ccccc23)cc1

InChI Key

Data  28 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044657   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044657(CHEMBL3353347 | US10358436, Example A24 | US990780...)
Affinity DataIC50: <100nMAssay Description:PLK3 inhibition was determined using the Z-Lyte assay kit from Invitrogen (cat #PV3802). The assay was performed using the recommended manufacturer&#...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044657(CHEMBL3353347 | US10358436, Example A24 | US990780...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FLT3 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM50044657(CHEMBL3353347 | US10358436, Example A24 | US990780...)
Affinity DataIC50: <100nMAssay Description:The enzymatic activity of FLT3 was determined using the Z-Lyte assay kit from Invitrogen (Invitrogen cat #PV3191). The assay was performed using the ...More data for this Ligand-Target Pair
In DepthDetails US Patent